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Disrupted in schizophrenia 1 (DISC1) L100P mutants have impaired activity-dependent plasticity in vivo and in vitro

Major neuropsychiatric disorders are genetically complex but share overlapping etiology. Mice mutant for rare, highly penetrant risk variants can be useful in dissecting the molecular mechanisms involved. The gene disrupted in schizophrenia 1 (DISC1) has been associated with increased risk for neuro...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Transl Psychiatry
Main Authors: Tropea, D, Molinos, I, Petit, E, Bellini, S, Nagakura, I, O'Tuathaigh, C, Schorova, L, Mitchell, K J, Waddington, J, Sur, M, Gill, M, Corvin, A P
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068880/
https://ncbi.nlm.nih.gov/pubmed/26756905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2015.206
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