Disrupted in schizophrenia 1 (DISC1) L100P mutants have impaired activity-dependent plasticity in vivo and in vitro

Major neuropsychiatric disorders are genetically complex but share overlapping etiology. Mice mutant for rare, highly penetrant risk variants can be useful in dissecting the molecular mechanisms involved. The gene disrupted in schizophrenia 1 (DISC1) has been associated with increased risk for neuro...

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Bibliografiske detaljer
Udgivet i:Transl Psychiatry
Main Authors: Tropea, D, Molinos, I, Petit, E, Bellini, S, Nagakura, I, O'Tuathaigh, C, Schorova, L, Mitchell, K J, Waddington, J, Sur, M, Gill, M, Corvin, A P
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068880/
https://ncbi.nlm.nih.gov/pubmed/26756905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2015.206
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