Disrupted-in-schizophrenia1 (DISC1) L100P mutation alters synaptic transmission and plasticity in the hippocampus and causes recognition memory deficits

Disrupted-in-schizophrenia 1(DISC1) is a promising candidate susceptibility gene for a spectrum of psychiatric illnesses that share cognitive impairments in common, including schizophrenia, bipolar disorder and major depression. Here we report that DISC1 L100P homozygous mutant shows normal anxiety-...

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Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Cui, Lin, Sun, Wei, Yu, Ming, Li, Nan, Guo, Li, Gu, Huating, Zhou, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059944/
https://ncbi.nlm.nih.gov/pubmed/27729083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-016-0270-y
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