A Synthetic Dosage Lethal Genetic Interaction Between CKS1B and PLK1 Is Conserved in Yeast and Human Cancer Cells

The CKS1B gene located on chromosome 1q21 is frequently amplified in breast, lung, and liver cancers. CKS1B codes for a conserved regulatory subunit of cyclin–CDK complexes that function at multiple stages of cell cycle progression. We used a high throughput screening protocol to mimic cancer-relate...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Genetics
Autors principals: Reid, Robert J. D., Du, Xing, Sunjevaric, Ivana, Rayannavar, Vinayak, Dittmar, John, Bryant, Eric, Maurer, Matthew, Rothstein, Rodney
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2016
Matèries:
Investigations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068864/
https://ncbi.nlm.nih.gov/pubmed/27558135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.190231
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars