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Intracellular inhibition of hepatitis C virus (HCV) internal ribosomal entry site (IRES)-dependent translation by peptide nucleic acids (PNAs) and locked nucleic acids (LNAs)

Hepatitis C virus (HCV) is the major etiological agent of non-A, non-B hepatitis. Current therapies are not effective in all patients and can result in the generation of resistant mutants, leading to a need for new therapeutic options. HCV has an RNA genome that contains a well-defined and highly co...

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Detalhes bibliográficos
Main Authors: Nulf, Christopher J., Corey, David
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC506796/
https://ncbi.nlm.nih.gov/pubmed/15263060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh706
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