A Small Yeast RNA Blocks Hepatitis C Virus Internal Ribosome Entry Site (HCV IRES)-Mediated Translation and Inhibits Replication of a Chimeric Poliovirus under Translational Control of the HCV IRES Element

Hepatitis C virus (HCV) infection frequently leads to chronic hepatitis and cirrhosis of the liver and has been linked to development of hepatocellular carcinoma. We previously identified a small yeast RNA (IRNA) capable of specifically inhibiting poliovirus (PV) internal ribosome entry site (IRES)-...

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Detalhes bibliográficos
Main Authors: Das, Saumitra, Ott, Michael, Yamane, Akemi, Tsai, Weimin, Gromeier, Matthias, Lahser, Frederick, Gupta, Sanjeev, Dasgupta, Asim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC110227/
https://ncbi.nlm.nih.gov/pubmed/9621022
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