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Epigenetic regulation of human DCLK-1 gene during colon-carcinogenesis: clinical and mechanistic implications
Colorectal carcinogenesis is a multi-step process. While ~25% of colorectal cancers (CRCs) arise in patients with a family history (genetic predisposition), ~75% of CRCs are due to age-associated accumulation of epigenetic alterations which can result in the suppression of key tumor suppressor genes...
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| 出版年: | Stem Cell Investig |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
AME Publishing Company
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5067362/ https://ncbi.nlm.nih.gov/pubmed/27777940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/sci.2016.09.07 |
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