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Leveraging large-scale behavioral profiling in zebrafish to explore neuroactive polypharmacology
Many psychiatric drugs modulate the nervous system through multi-target mechanisms. However, systematic identification of multi-target compounds has been difficult using traditional in vitro screening assays. New approaches to phenotypic profiling in zebrafish can help researchers identify novel com...
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| Publicat a: | ACS Chem Biol |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5067259/ https://ncbi.nlm.nih.gov/pubmed/26845413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00800 |
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