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NOX2 drives M1-like microglial/macrophage activation and neurodegeneration following experimental traumatic brain injury

Following traumatic brain injury (TBI), activation of microglia and peripherally derived inflammatory macrophages occurs in association with tissue damage. This neuroinflammatory response may have beneficial or detrimental effects on neuronal survival, depending on the functional polarization of the...

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Detalhes bibliográficos
Publicado no:Brain Behav Immun
Main Authors: Kumar, Alok, Barrett, James P., Alvarez-Croda, Dulce-Mariely, Stoica, Bogdan A., Faden, Alan I., Loane, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067217/
https://ncbi.nlm.nih.gov/pubmed/27477920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2016.07.158
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