NOX2 drives M1-like microglial/macrophage activation and neurodegeneration following experimental traumatic brain injury

Following traumatic brain injury (TBI), activation of microglia and peripherally derived inflammatory macrophages occurs in association with tissue damage. This neuroinflammatory response may have beneficial or detrimental effects on neuronal survival, depending on the functional polarization of the...

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Publicado en:Brain Behav Immun
Autores principales: Kumar, Alok, Barrett, James P., Alvarez-Croda, Dulce-Mariely, Stoica, Bogdan A., Faden, Alan I., Loane, David J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067217/
https://ncbi.nlm.nih.gov/pubmed/27477920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2016.07.158
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