Loading...
Oxazin-5-Ones as a Novel Class of Penicillin Binding Protein Inhibitors: Design, Synthesis and Structure Activity Relationship
Penicillin binding proteins (PBPs) are normal constituents of bacterial which are absent in mammalian cells. The theoretical binding modes of known oxazin-5-ones toward the protein were used as a guide to synthesis new inhibitors. Structural studies of protein-ligand complexes revealed that conforma...
Na minha lista:
| Udgivet i: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2016
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5066960/ https://ncbi.nlm.nih.gov/pubmed/27749913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163467 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|