Angular Phenozaxine Ethers as Potent Multi-microbial Targets Inhibitors: Design, Synthesis, and Molecular Docking Studies

The reaction of diaza-5H-benzo[a]phenoxazin-5-one and 5H-benzo[a]phenoxazin-5-one with various phenols catalyzed by Pd/t-BuXPhos/K(3)PO(4) system gave previously unknown ether derivatives (7a–f and 8a–f) in good yields. UV-visible, FTIR, and (1)H NMR data were used to confirm structures of the synth...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Ezeokonkwo, Mercy A., Ogbonna, Onyinyechi N., Okafor, Sunday N., Godwin-Nwakwasi, Evelyn U., Ibeanu, Fidelia N., Okoro, Uchechukwu C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712349/
https://ncbi.nlm.nih.gov/pubmed/29238706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2017.00107
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