Novel anti-inflammatory and analgesic agents: synthesis, molecular docking and in vivo studies

Twelve new derivatives of benzothiazole bearing benzenesulphonamide and carboxamide were synthesised and investigated for their in vivo anti-inflammatory, analgesic and ulcerogenic activities. Molecular docking showed an excellent binding interaction of the synthesised compounds with the receptors,...

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Vydáno v:J Enzyme Inhib Med Chem
Hlavní autoři: Ugwu, David Izuchukwu, Okoro, Uchechukwu Christopher, Ukoha, Pius Onyeoziri, Gupta, Astha, Okafor, Sunday N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7011796/
https://ncbi.nlm.nih.gov/pubmed/29372659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1426573
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