Targeted suppression of autoreactive CD8(+) T-cell activation using blocking anti-CD8 antibodies

CD8(+) T-cells play a role in the pathogenesis of autoimmune diseases such as multiple sclerosis and type 1 diabetes. However, drugs that target the entire CD8(+) T-cell population are not desirable because the associated lack of specificity can lead to unwanted consequences, most notably an enhance...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Clement, Mathew, Pearson, James A., Gras, Stephanie, van den Berg, Hugo A., Lissina, Anya, Llewellyn-Lacey, Sian, Willis, Mark D., Dockree, Tamsin, McLaren, James E., Ekeruche-Makinde, Julia, Gostick, Emma, Robertson, Neil P., Rossjohn, Jamie, Burrows, Scott R., Price, David A., Wong, F. Susan, Peakman, Mark, Skowera, Ania, Wooldridge, Linda
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066216/
https://ncbi.nlm.nih.gov/pubmed/27748447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35332
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados