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Huperzine A Provides Robust and Sustained Protection against Induced Seizures in Scn1a Mutant Mice
De novo loss-of-function mutations in the voltage-gated sodium channel (VGSC) SCN1A (encoding Na(v)1.1) are the main cause of Dravet syndrome (DS), a catastrophic early-life encephalopathy associated with prolonged and recurrent early-life febrile seizures (FSs), refractory afebrile epilepsy, cognit...
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| Publicado no: | Front Pharmacol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5065986/ https://ncbi.nlm.nih.gov/pubmed/27799911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00357 |
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