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In silico and in vitro methods to identify Ebola virus VP35-dsRNA inhibitors

Ebola virus continues to be problematic as sporadic outbreaks in Africa continue to arise, and as terrorist organizations have considered the virus for bioterrorism use. Several proteins within the virus have been targeted for antiviral chemotherapy, including VP35, a dsRNA binding protein that prom...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Bioorg Med Chem
Main Authors: Glanzer, Jason G., Byrne, Brendan M., McCoy, Aaron M., James, Ben J., Frank, Joshua D., Oakley, Greg G.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065780/
https://ncbi.nlm.nih.gov/pubmed/27642076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2016.08.065
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