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In silico and in vitro methods to identify Ebola virus VP35-dsRNA inhibitors

Ebola virus continues to be problematic as sporadic outbreaks in Africa continue to arise, and as terrorist organizations have considered the virus for bioterrorism use. Several proteins within the virus have been targeted for antiviral chemotherapy, including VP35, a dsRNA binding protein that prom...

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Bibliografiske detaljer
Udgivet i:Bioorg Med Chem
Main Authors: Glanzer, Jason G., Byrne, Brendan M., McCoy, Aaron M., James, Ben J., Frank, Joshua D., Oakley, Greg G.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065780/
https://ncbi.nlm.nih.gov/pubmed/27642076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2016.08.065
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