Macrophage-derived extracellular vesicle-packaged WNTs rescue intestinal stem cells and enhance survival after radiation injury

WNT/β-catenin signalling is crucial for intestinal homoeostasis. The intestinal epithelium and stroma are the major source of WNT ligands but their origin and role in intestinal stem cell (ISC) and epithelial repair remains unknown. Macrophages are a major constituent of the intestinal stroma. Here,...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Saha, Subhrajit, Aranda, Evelyn, Hayakawa, Yoku, Bhanja, Payel, Atay, Safinur, Brodin, N Patrik, Li, Jiufeng, Asfaha, Samuel, Liu, Laibin, Tailor, Yagnesh, Zhang, Jinghang, Godwin, Andrew K., Tome, Wolfgang A., Wang, Timothy C., Guha, Chandan, Pollard, Jeffrey W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065628/
https://ncbi.nlm.nih.gov/pubmed/27734833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13096
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados