Low intensity focused ultrasound (LOFU) modulates unfolded protein response and sensitizes prostate cancer to 17AAG

The hypoxic tumor microenvironment generates oxidative Endoplasmic Reticulum (ER) stress, resulting in protein misfolding and unfolded protein response (UPR). UPR induces several molecular chaperones including heat-shock protein 90 (HSP90), which corrects protein misfolding and improves survival of...

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Detalhes bibliográficos
Publicado no:Oncoscience
Main Authors: Saha, Subhrajit, Bhanja, Payel, Partanen, Ari, Zhang, Wei, Liu, Laibin, Tomé, Wolfgang, Guha, Chandan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284617/
https://ncbi.nlm.nih.gov/pubmed/25594042
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