Low intensity focused ultrasound (LOFU) modulates unfolded protein response and sensitizes prostate cancer to 17AAG

The hypoxic tumor microenvironment generates oxidative Endoplasmic Reticulum (ER) stress, resulting in protein misfolding and unfolded protein response (UPR). UPR induces several molecular chaperones including heat-shock protein 90 (HSP90), which corrects protein misfolding and improves survival of...

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Spremljeno u:
Bibliografski detalji
Izdano u:Oncoscience
Glavni autori: Saha, Subhrajit, Bhanja, Payel, Partanen, Ari, Zhang, Wei, Liu, Laibin, Tomé, Wolfgang, Guha, Chandan
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2014
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284617/
https://ncbi.nlm.nih.gov/pubmed/25594042
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