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TLR9 Agonist Protects Mice from Radiation-Induced Gastrointestinal Syndrome
PURPOSE: Radiation-induced gastrointestinal syndrome (RIGS) is due to the clonogenic loss of crypt cells and villi depopulation, resulting in disruption of mucosal barrier, bacterial invasion, inflammation and sepsis. Intestinal macrophages could recognize invading bacterial DNA via TLR9 receptors a...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3251576/ https://ncbi.nlm.nih.gov/pubmed/22238604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029357 |
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