TLR9 Agonist Protects Mice from Radiation-Induced Gastrointestinal Syndrome

PURPOSE: Radiation-induced gastrointestinal syndrome (RIGS) is due to the clonogenic loss of crypt cells and villi depopulation, resulting in disruption of mucosal barrier, bacterial invasion, inflammation and sepsis. Intestinal macrophages could recognize invading bacterial DNA via TLR9 receptors a...

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Detaylı Bibliyografya
Asıl Yazarlar: Saha, Subhrajit, Bhanja, Payel, Liu, Laibin, Alfieri, Alan A., Yu, Dong, Kandimalla, Ekambar R., Agrawal, Sudhir, Guha, Chandan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251576/
https://ncbi.nlm.nih.gov/pubmed/22238604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029357
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