Calcium Signalling Triggered by NAADP in T Cells Determines Cell Shape and Motility During Immune Synapse Formation

Nicotinic acid adenine dinucleotide phosphate (NAADP) has been implicated as an initial Ca(2+) trigger in T cell Ca(2+) signalling, but its role in formation of the immune synapse in CD4(+) effector T cells has not been analysed. CD4(+) T cells are activated by the interaction with peptide-MHCII com...

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Vydáno v:Messenger (Los Angel)
Hlavní autoři: Nebel, Merle, Zhang, Bo, Odoardi, Francesca, Flügel, Alexander, Potter, Barry V. L., Guse, Andreas H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065091/
https://ncbi.nlm.nih.gov/pubmed/27747143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1166/msr.2015.1045
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