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BK Polyomavirus Replication in Renal Tubular Epithelial Cells Is Inhibited by Sirolimus, but Activated by Tacrolimus Through a Pathway Involving FKBP‐12

BK polyomavirus (BKPyV) replication causes nephropathy and premature kidney transplant failure. Insufficient BKPyV‐specific T cell control is regarded as a key mechanism, but direct effects of immunosuppressive drugs on BKPyV replication might play an additional role. We compared the effects of mamm...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Transplant
Hauptverfasser: Hirsch, H. H., Yakhontova, K., Lu, M., Manzetti, J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064607/
https://ncbi.nlm.nih.gov/pubmed/26639422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13541
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