Cloning of cDNAs of the MLL gene that detect DNA rearrangements and altered RNA transcripts in human leukemic cells with 11q23 translocations.

Recurring chromosomal abnormalities involving translocations at chromosome 11 band q23 are associated with human myeloid and lymphoid leukemia as well as lymphoma. We have identified the gene located at this break-point and have named it MLL (for myeloid-lymphoid, or mixed-lineage, leukemia). The t(...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	McCabe, N R, Burnett, R C, Gill, H J, Thirman, M J, Mbangkollo, D, Kipiniak, M, van Melle, E, Ziemin-van der Poel, S, Rowley, J D, Diaz, M O
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1992
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50643/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1465401/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.24.11794
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!