Cloning of cDNAs of the MLL gene that detect DNA rearrangements and altered RNA transcripts in human leukemic cells with 11q23 translocations.

Recurring chromosomal abnormalities involving translocations at chromosome 11 band q23 are associated with human myeloid and lymphoid leukemia as well as lymphoma. We have identified the gene located at this break-point and have named it MLL (for myeloid-lymphoid, or mixed-lineage, leukemia). The t(...

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Bibliographic Details
Main Authors: McCabe, N R, Burnett, R C, Gill, H J, Thirman, M J, Mbangkollo, D, Kipiniak, M, van Melle, E, Ziemin-van der Poel, S, Rowley, J D, Diaz, M O
Format: Artigo
Language:Inglês
Published: 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC50643/
https://ncbi.nlm.nih.gov/pubmed/1465401
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