11q23 translocations split the "AT-hook" cruciform DNA-binding region and the transcriptional repression domain from the activation domain of the mixed-lineage leukemia (MLL) gene.

Lignende værker

• Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias.
  af: Ziemin-van der Poel, S, et al.
  Udgivet: (1991)
• MSF (MLL septin-like fusion), a fusion partner gene of MLL, in a therapy-related acute myeloid leukemia with a t(11;17)(q23;q25)
  af: Osaka, Mitsuhiko, et al.
  Udgivet: (1999)
• Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias
  Udgivet: (1992)
• Acute mixed-lineage leukemia t(4;11)(q21;q23) generates an MLL-AF4 fusion product.
  af: Domer, P H, et al.
  Udgivet: (1993)
• Philadelphia chromosome-negative acute myeloid leukemia with 11q23/MLL translocation in a patient with chronic myelogenous leukemia
  af: Jaitly, Vanya, et al.
  Udgivet: (2015)