11q23 translocations split the "AT-hook" cruciform DNA-binding region and the transcriptional repression domain from the activation domain of the mixed-lineage leukemia (MLL) gene.

Eitemau Tebyg

• Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias.
  gan: Ziemin-van der Poel, S, et al.
  Cyhoeddwyd: (1991)
• MSF (MLL septin-like fusion), a fusion partner gene of MLL, in a therapy-related acute myeloid leukemia with a t(11;17)(q23;q25)
  gan: Osaka, Mitsuhiko, et al.
  Cyhoeddwyd: (1999)
• Acute mixed-lineage leukemia t(4;11)(q21;q23) generates an MLL-AF4 fusion product.
  gan: Domer, P H, et al.
  Cyhoeddwyd: (1993)
• First description of the t(10;11)(q22;q23)/MLL-TET1 translocation in a T-cell lymphoblastic lymphoma, with subsequent lineage switch to acute myelomonocytic myeloid leukemia
  gan: Ittel, Antoine, et al.
  Cyhoeddwyd: (2013)
• MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3)
  gan: Sobulo, Olatoyosi M., et al.
  Cyhoeddwyd: (1997)