Rational Design of a Parthenolide-based Drug Regimen That Selectively Eradicates Acute Myelogenous Leukemia Stem Cells

Although multidrug approaches to cancer therapy are common, few strategies are based on rigorous scientific principles. Rather, drug combinations are largely dictated by empirical or clinical parameters. In the present study we developed a strategy for rational design of a regimen that selectively t...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Pei, Shanshan, Minhajuddin, Mohammad, D'Alessandro, Angelo, Nemkov, Travis, Stevens, Brett M., Adane, Biniam, Khan, Nabilah, Hagen, Fred K., Yadav, Vinod K., De, Subhajyoti, Ashton, John M., Hansen, Kirk C., Gutman, Jonathan A., Pollyea, Daniel A., Crooks, Peter A., Smith, Clayton, Jordan, Craig T.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2016
主題:
Molecular Bases of Disease
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063982/
https://ncbi.nlm.nih.gov/pubmed/27573247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.750653
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