Regulation of Amyloid β Oligomer Binding to Neurons and Neurotoxicity by the Prion Protein-mGluR5 Complex

The prion protein (PrP(C)) has been suggested to operate as a scaffold/receptor protein in neurons, participating in both physiological and pathological associated events. PrP(C), laminin, and metabotropic glutamate receptor 5 (mGluR5) form a protein complex on the plasma membrane that can trigger s...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Beraldo, Flavio H., Ostapchenko, Valeriy G., Caetano, Fabiana A., Guimaraes, Andre L. S., Ferretti, Giulia D. S., Daude, Nathalie, Bertram, Lisa, Nogueira, Katiane O. P. C., Silva, Jerson L., Westaway, David, Cashman, Neil R., Martins, Vilma R., Prado, Vania F., Prado, Marco A. M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2016
Gaiak:
Molecular Bases of Disease
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063978/
https://ncbi.nlm.nih.gov/pubmed/27563063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.738286
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