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Polq-mediated end joining is essential for surviving DNA double-strand breaks during early zebrafish development
Error-prone repair of DNA double-strand breaks (DSBs) has been postulated to occur through classical non-homologous end joining (NHEJ) in systems ranging from nematode somatic tissues to zebrafish embryos. Contrary to this model, we show that zebrafish embryos mutant for DNA polymerase theta (Polq),...
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| Pubblicato in: | Cell Rep |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5063659/ https://ncbi.nlm.nih.gov/pubmed/27149851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.03.072 |
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