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HPLC method development, validation, and impurity characterization of a potent antitumor nucleoside, T-dCyd (NSC 764276)
An HPLC method for the assay of an anticancer nucleoside, 4’-thio-2’-deoxycytidine (T–dCyd, NSC 764276), has been developed and validated. The stress testing of T-dCyd was carried out in accordance with ICH guidelines Q1A (R2) under acidic, alkaline, oxidative, thermolytic, and photolytic conditions...
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| Publicado no: | J Pharm Biomed Anal |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5063648/ https://ncbi.nlm.nih.gov/pubmed/27661436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2016.08.034 |
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