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Mouse genetic background contributes to hepatocyte susceptibility to Fas-mediated apoptosis
Liver disease progression is modulated by genetic modifiers in mouse strains and across human races and ethnicities. We hypothesized that hepatocyte culture duration and genetic background regulate hepatocyte susceptibility to apoptosis. Hepatocytes were isolated from FVB/N, C57BL/6, and C3H/He mice...
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| Publié dans: | Mol Biol Cell |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Cell Biology
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5063609/ https://ncbi.nlm.nih.gov/pubmed/27535425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-06-0423 |
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