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Mouse genetic background contributes to hepatocyte susceptibility to Fas-mediated apoptosis

Liver disease progression is modulated by genetic modifiers in mouse strains and across human races and ethnicities. We hypothesized that hepatocyte culture duration and genetic background regulate hepatocyte susceptibility to apoptosis. Hepatocytes were isolated from FVB/N, C57BL/6, and C3H/He mice...

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Foilsithe in:Mol Biol Cell
Main Authors: Weerasinghe, Sujith V. W., Park, Min-Jung, Portney, Daniel A., Omary, M. Bishr
Formáid: Artigo
Teanga:Inglês
Foilsithe: The American Society for Cell Biology 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063609/
https://ncbi.nlm.nih.gov/pubmed/27535425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-06-0423
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