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Keratin impact on PKCδ- and ASMase-mediated regulation of hepatocyte lipid raft size – implication for FasR-associated apoptosis

Keratins are epithelial cell intermediate filament (IF) proteins that are expressed as pairs in a cell-differentiation-regulated manner. Hepatocytes express the keratin 8 and 18 pair (denoted K8/K18) of IFs, and a loss of K8 or K18, as in K8-null mice, leads to degradation of the keratin partner. We...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Gilbert, Stéphane, Loranger, Anne, Omary, M. Bishr, Marceau, Normand
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047704/
https://ncbi.nlm.nih.gov/pubmed/27422101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.171124
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