Thrombospondin expression in myofibers stabilizes muscle membranes

Skeletal muscle is highly sensitive to mutations in genes that participate in membrane stability and cellular attachment, which often leads to muscular dystrophy. Here we show that Thrombospondin-4 (Thbs4) regulates skeletal muscle integrity and its susceptibility to muscular dystrophy through organ...

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Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Vanhoutte, Davy, Schips, Tobias G, Kwong, Jennifer Q, Davis, Jennifer, Tjondrokoesoemo, Andoria, Brody, Matthew J, Sargent, Michelle A, Kanisicak, Onur, Yi, Hong, Gao, Quan Q, Rabinowitz, Joseph E, Volk, Talila, McNally, Elizabeth M, Molkentin, Jeffery D
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2016
Onderwerpen:
Cell Biology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063588/
https://ncbi.nlm.nih.gov/pubmed/27669143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.17589
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