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Genetic overexpression of Serpina3n attenuates muscular dystrophy in mice
Muscular dystrophy (MD) is associated with mutations in genes that stabilize the myofiber plasma membrane, such as through the dystrophin–glycoprotein complex (DGC). Instability of this complex or defects in membrane repair/integrity leads to calcium influx and myofiber necrosis leading to progressi...
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| Publicado no: | Hum Mol Genet |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4764199/ https://ncbi.nlm.nih.gov/pubmed/26744329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw005 |
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