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Myofiber-specific inhibition of TGFβ signaling protects skeletal muscle from injury and dystrophic disease in mice

Muscular dystrophy (MD) is a disease characterized by skeletal muscle necrosis and the progressive accumulation of fibrotic tissue. While transforming growth factor (TGF)-β has emerged as central effector of MD and fibrotic disease, the cell types in diseased muscle that underlie TGFβ-dependent path...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Accornero, Federica, Kanisicak, Onur, Tjondrokoesoemo, Andoria, Attia, Aria C., McNally, Elizabeth M., Molkentin, Jeffery D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271062/
https://ncbi.nlm.nih.gov/pubmed/25106553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu413
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