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Dynamic ASXL1 Exon Skipping and Alternative Circular Splicing in Single Human Cells
Circular RNAs comprise a poorly understood new class of noncoding RNA. In this study, we used a combination of targeted deletion, high-resolution splicing detection, and single-cell sequencing to deeply probe ASXL1 circular splicing. We found that efficient circular splicing required the canonical t...
Shranjeno v:
izdano v: | PLoS One |
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Main Authors: | , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Public Library of Science
2016
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5063410/ https://ncbi.nlm.nih.gov/pubmed/27736885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164085 |
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