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Atypical 5′ Splice Sites Cause CFTR Exon 9 To Be Vulnerable to Skipping

The molecular basis of the skipping of constitutive exons in many messenger RNAs is not fully understood. A well-studied example is exon 9 of the human cystic fibrosis transmembrane conductance regulator gene (CFTR), in which an abbreviated polypyrimidine tract between the branch point A and the 3′...

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Detalhes bibliográficos
Main Authors: Hefferon, Timothy W., Broackes-Carter, Fiona C., Harris, Ann, Cutting, Garry R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC379162/
https://ncbi.nlm.nih.gov/pubmed/12068373
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