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A variable dinucleotide repeat in the CFTR gene contributes to phenotype diversity by forming RNA secondary structures that alter splicing

Dinucleotide repeats are ubiquitous features of eukaryotic genomes that are not generally considered to have functional roles in gene expression. However, the highly variable nature of dinucleotide repeats makes them particularly interesting candidates for modifiers of RNA splicing when they are fou...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Hefferon, Timothy W., Groman, Joshua D., Yurk, Catherine E., Cutting, Garry R.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2004
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC373492/
https://ncbi.nlm.nih.gov/pubmed/14993601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400182101
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