Dysregulated TGF-β Production Underlies the Age-Related Vulnerability to Chikungunya Virus

Chikungunya virus (CHIKV) is a re-emerging global pathogen with pandemic potential, which causes fever, rash and debilitating arthralgia. Older adults over 65 years are particularly susceptible to severe and chronic CHIKV disease (CHIKVD), accounting for >90% of all CHIKV-related deaths. There ar...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Uhrlaub, Jennifer L., Pulko, Vesna, DeFilippis, Victor R., Broeckel, Rebecca, Streblow, Daniel N., Coleman, Gary D., Park, Byung S., Lindo, John F., Vickers, Ivan, Anzinger, Joshua J., Nikolich-Žugich, Janko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063327/
https://ncbi.nlm.nih.gov/pubmed/27736984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005891
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