The CRF1 Antagonist Verucerfont in Anxious Alcohol-Dependent Women: Translation of Neuroendocrine, But not of Anti-Craving Effects

Blockade of corticotropin-releasing factor receptor 1 (CRF1) suppresses stress-induced alcohol seeking in rodents, but clinical translation remains. Here, we first showed that the CRF1 antagonist verucerfont potently blocks hypothalamic-pituitary adrenal (HPA) axis activation in adrenalectomized rat...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Neuropsychopharmacology
Auteurs principaux: Schwandt, Melanie L, Cortes, Carlos R, Kwako, Laura E, George, David T, Momenan, Reza, Sinha, Rajita, Grigoriadis, Dimitri E, Pich, Emilio Merlo, Leggio, Lorenzo, Heilig, Markus
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5061889/
https://ncbi.nlm.nih.gov/pubmed/27109623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2016.61
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires