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A hybrid NMR/SAXS-based approach for discriminating oligomeric protein interfaces using Rosetta
Oligomeric proteins are important targets for structure determination in solution. While in most cases the fold of individual subunits can be determined experimentally, or predicted by homology-based methods, protein-protein interfaces are challenging to determine de novo using conventional NMR stru...
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Publicado no: | Proteins |
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Main Authors: | , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5061451/ https://ncbi.nlm.nih.gov/pubmed/25388768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24719 |
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