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Improving NMR Protein Structure Quality by Rosetta Refinement: A Molecular Replacement Study

The structure of human protein HSPC034 has been determined by both solution NMR spectroscopy and X-ray crystallography. Refinement of the NMR structure ensemble, using a Rosetta protocol in the absence of NMR restraints, resulted in significant improvements not only in structure quality, but also in...

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Bibliografiske detaljer
Main Authors: Ramelot, Theresa A., Raman, Srivatsan, Kuzin, Alexandre P., Xiao, Rong, Ma, Li-Chung, Acton, Thomas B., Hunt, John F., Montelione, Gaetano T., Baker, David, Kennedy, Michael A.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878636/
https://ncbi.nlm.nih.gov/pubmed/18816799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22229
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