A hybrid NMR/SAXS-based approach for discriminating oligomeric protein interfaces using Rosetta

Oligomeric proteins are important targets for structure determination in solution. While in most cases the fold of individual subunits can be determined experimentally, or predicted by homology-based methods, protein-protein interfaces are challenging to determine de novo using conventional NMR stru...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proteins
Main Authors: Rossi, Paolo, Shi, Lei, Liu, Gaohua, Barbieri, Christopher M., Lee, Hsiau-Wei, Grant, Thomas D., Luft, Joseph R., Xiao, Rong, Acton, Thomas B., Snell, Edward H., Montelione, Gaetano T., Baker, David, Lange, Oliver F., Sgourakis, Nikolaos G.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5061451/
https://ncbi.nlm.nih.gov/pubmed/25388768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24719
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