Nitric oxide-mediated apoptosis of neutrophils through caspase-8 and caspase-3-dependent mechanism

Neutrophils play an indispensable role in killing of invading pathogens by enhancing reactive oxygen species (ROS) and NO generation, and subsequently undergoing apoptosis. Unlike ROS/NOX2, role of NO/NOS still remains undefined in the apoptosis of neutrophils (PMNs) and the present study attempts t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Dis
Hauptverfasser: Dubey, Megha, Nagarkoti, Sheela, Awasthi, Deepika, Singh, Abhishek K, Chandra, Tulika, Kumaravelu, J, Barthwal, Manoj K, Dikshit, Madhu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059853/
https://ncbi.nlm.nih.gov/pubmed/27584786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.248
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