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Role of pyruvate kinase M2 in oxidized LDL-induced macrophage foam cell formation and inflammation

Pyruvate kinase M2 (PKM2) links metabolic and inflammatory dysfunction in atherosclerotic coronary artery disease; however, its role in oxidized LDL (Ox-LDL)-induced macrophage foam cell formation and inflammation is unknown and therefore was studied. In recombinant mouse granulocyte-macrophage colo...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Kumar, Amit, Gupta, Priya, Rana, Minakshi, Chandra, Tulika, Dikshit, Madhu, Barthwal, Manoj Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053835/
https://ncbi.nlm.nih.gov/pubmed/31988148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA119000382
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