PKCδ-IRAK1 axis regulates oxidized LDL-induced IL-1β production in monocytes

This study examined the role of interleukin (IL)-1 receptor-associated kinase (IRAK) and protein kinase C (PKC) in oxidized LDL (Ox-LDL)-induced monocyte IL-1β production. In THP1 cells, Ox-LDL induced time-dependent secretory IL-1β and IRAK1 activity; IRAK4, IRAK3, and CD36 protein expression; PKCδ...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Tiwari, Rajiv Lochan, Singh, Vishal, Singh, Ankita, Rana, Minakshi, Verma, Anupam, Kothari, Nikhil, Kohli, Monica, Bogra, Jaishri, Dikshit, Madhu, Barthwal, Manoj Kumar
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2014
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076070/
https://ncbi.nlm.nih.gov/pubmed/24792928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M045658
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky