A Standardized Chemically Modified Curcuma longa Extract Modulates IRAK-MAPK Signaling in Inflammation and Potentiates Cytotoxicity

The TLR/IL-1R pathway is a critical signaling module that is misregulated in pathologies like inflammation and cancer. Extracts from turmeric (Curcuma longa L.) enriched in curcumin and carbonyls like turmerones have been shown to exert potent anti-inflammatory effects. The present study evaluated t...

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Опубликовано в: :Front Pharmacol
Главные авторы: Rana, Minakshi, Maurya, Preeti, Reddy, Sukka S., Singh, Vishal, Ahmad, Hafsa, Dwivedi, Anil K., Dikshit, Madhu, Barthwal, Manoj K.
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2016
Предметы:
Pharmacology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959270/
https://ncbi.nlm.nih.gov/pubmed/27504095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00223
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