Glutathione deficiency increases hepatic ascorbic acid synthesis in adult mice.
Glutathione deficiency, induced in adult mice by administering buthionine sulfoximine (an inhibitor of glutathione synthesis), led to a rapid and substantial increase in ascorbate in the liver. This effect was apparent 2-4 hr after giving the inhibitor; subsequently, the level of ascorbate decreased...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50593/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1454849/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.23.11566 |
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